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Originally published April 9, 2021
Last updated November 6, 2025
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Most people have experienced diarrhea at some point in their lives. It鈥檚 not fun to be running to the bathroom, wondering what happened to upset your intestines so much. Worse yet, diarrhea can sometimes have serious complications or even be chronic.
Here are some of the most common causes of diarrhea and when you should see a doctor about your symptoms.
Food that is contaminated with bacteria, such as E. coli, salmonella and listeria, can give you , which often causes diarrhea. Viruses, such as norovirus and rotavirus, can give you viral , which also causes diarrhea. (You may call this the stomach flu, but it鈥檚 not really a flu at all.) occurs when people travel to a country where these infections are more common.
How do bacteria and viruses lead to diarrhea?
鈥淚nfectious bacteria or viruses commonly colonize the lining of your intestines and release toxins,鈥 explains Matthew Jung, MD, an internal medicine physician with 喵咪社区. 鈥淭hese toxins cause the lining of your intestines to secrete an excessive amount of electrolytes and fluid, which results in diarrhea.鈥
Bacteria and viruses can also cause inflammation along the lining of your intestines, which also results in diarrhea, according to Dr. Jung.
“The diarrhea can sometimes be bloody,” he adds.
Although most people associate COVID-19 with fever and respiratory symptoms, it can also cause gastrointestinal disturbances. But what鈥檚 the link between diarrhea and COVID-19?
鈥淩esearch indicates that the SARS-CoV-2 virus 鈥 the virus that causes COVID-19 鈥 has an affinity for cell receptors that are present both in the lungs as well as parts of the gastrointestinal tract,鈥 Dr. Jung says. 鈥淚nflammation in the lungs can produce the typical respiratory symptoms we have come to expect from a COVID-19 infection, and inflammation of the gastrointestinal tract is likely the cause of the diarrhea that some people with COVID-19 experience.鈥
Both food allergies and food intolerances can cause diarrhea.
鈥淔ood allergies are the result of the immune system鈥檚 excessive response to normal food,鈥 Dr. Jung says. 鈥淎 food intolerance, on the other hand, is generally the result of a gastrointestinal error in the way that food is processed.鈥
is a common food intolerance.
鈥淣ormally, an enzyme called lactase breaks down the sugar lactose so that it can be absorbed by the small intestine,鈥 Dr. Jung says. 鈥淏ut when there is a decreased production of lactase or when it is not working effectively, an excessive amount of lactose can enter the large intestine, where it gets broken down by the bacteria that lives there. Unfortunately, this bacteria breaks the lactose down in such a way that hydrogen gas is created, which results in bloating and diarrhea symptoms.鈥
An other carbohydrates can also cause diarrhea. These commonly include sugars like fructose, which is found in fruits or is added to juices and other sweet things, as well as sugar alcohols used in artificial sweeteners, such as sorbitol, mannitol and xylitol.
and are related autoimmune conditions that affect the gastrointestinal tract and can cause chronic diarrhea.
鈥淐rohn鈥檚 disease and ulcerative colitis are inflammatory bowel diseases (IBD) that cause inflammation in certain parts of the gastrointestinal tract,鈥 Dr. Jung says. 鈥淭his inflammation can interfere with the absorption of nutrients and carbohydrates and can cause diarrhea.鈥
IBD requires management by a doctor.
is another autoimmune condition that can lead to chronic diarrhea. When someone with celiac disease consumes the protein gluten, it can trigger inflammation in the small intestine, eventually damaging it.
IBS is a chronic condition that causes diarrhea, bloating and constipation.
鈥淭he exact mechanism by which IBS causes diarrhea is uncertain,鈥 Dr. Jung says. 鈥淚t鈥檚 considered a syndrome, which means it is a collection of symptoms that commonly occur together, instead of a particular disease with a specific cause.鈥
According to Dr. Jung, IBS likely results from several factors, and the cause of one person鈥檚 IBS may not be the same as another person鈥檚. He notes that the can range from how well food moves through the gastrointestinal system to intestinal inflammation, infection or even genetics.
Taking certain medications can sometimes result in unwanted side effects, like diarrhea. Antibiotics, for example, can disrupt the balance of bacteria in your intestines, which can cause diarrhea. Even more seriously, this imbalance can lead to a greater likelihood of an overload of the bacteria, Clostridioides difficile, or .
Antacids are another example of a medication that can cause diarrhea. Antacids containing , in particular, have a laxative effect.
If you start taking any medication and then have diarrhea, call your doctor.
Parasitic infection in the intestines can lead to diarrhea 鈥 and worse, sometimes these organisms stick around for a while, leading to chronic symptoms. This is uncommon in developed countries, like the United States, but people can pick up this type of infection while traveling to places where they are more common.
Parasites that commonly cause diarrhea include Cryptosporidium, often called , and Giardia duodenalis, or .
Most of the time, diarrhea from acute infections goes away on its own.
鈥淭he most important thing in these situations is to try to stay hydrated and monitor for worsening or persistence of symptoms,鈥 Dr. Jung says. 鈥淔or mild cases, beverages like fruit juices or sports drinks may be sufficient to keep you hydrated.鈥
However, if you experience any of the following with diarrhea, Dr. Jung recommends letting your doctor know:
He notes that it鈥檚 also best to contact your doctor if:
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