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Everyday Health

Are Hiccups a Sign of Something Serious?

Originally published September 12, 2019

Last updated June 28, 2025

Reading Time: 4 minutes

If your hiccups are chronic, they may be more than a temporary annoyance. Find out about the underlying medical conditions that may be causing them.

Hiccups can be frustrating, especially if they occur for what seems like no apparent reason. They鈥檙e usually temporary, though, and resolve on their own in a few minutes. But, while we typically think of hiccups as annoying but not serious, that might not always be the case. Read on to learn more about hiccups, what you can do about them and when you should see a doctor. 

What happens when you hiccup?聽

The physiological process of hiccupping is straightforward. It occurs when there is rapid contraction of your respiratory muscles such as your diaphragm, the muscle at the base of your lungs. This causes you to inhale quickly. When this happens, your vocal cords quickly close, which in turn causes the telltale 鈥渉ic鈥 sound. 

What causes hiccups?聽

Involuntary spasms of the diaphragm can occur when we eat too quickly (or too much), drink alcohol or drink carbonated beverages. Other causes can include eating something hot or spicy, a bloated stomach, abdominal surgery, certain medications or even just feeling nervous. 

鈥淔or the average person, the cause is probably some type of gastric distension,鈥 says Anisa Shaker, MD, a gastroenterologist with the 喵咪社区 Digestive Health Institute, part of 喵咪社区.  

How to stop hiccups聽

The first thing we usually turn to when it comes to alleviating hiccups are home remedies 鈥 and sometimes they actually do work! Special breathing exercises may provide some relief. Holding your breath or breathing into a paper bag, for instance, may help because it raises the content of carbon dioxide in the blood, and in doing so, quells hiccups.  

Anything that may stimulate the vagus nerve (which connects the brain to the stomach), such as sipping or gargling cold water, lightly pulling on your tongue or gently rubbing your eyes, may do the trick. 

While there鈥檚 no guaranteed way to prevent hiccups, you can take steps to reduce how often you get them. For those prone to hiccups, Dr. Shaker suggests avoiding known triggers, such as carbonated beverages, spicy foods, eating too fast or drinking too much alcohol. If your medications are causing the hiccups, your doctor can help recommend alternatives. 

Can hiccups be a sign of something serious?聽

Most hiccups are harmless and self-limiting, meaning they resolve quickly on their own, but knowing when they might be a warning sign is important. Chronic hiccups, in particular, can signal an underlying medical condition.  

Thankfully, most hiccups typically resolve within minutes or a few hours at most. Hiccups that last longer than 48 hours are much rarer, Dr. Shaker notes. 

Chronic hiccups can impact your quality of life if they interrupt your sleeping and eating patterns. 鈥淵ou probably should not be having hiccups when you鈥檙e asleep,鈥 Dr. Shaker says.  

In addition to causing weight loss, exhaustion and dehydration, chronic hiccups can cause other side effects including gastroesophageal reflux disease (also known as GERD), an irregular heartbeat, chest pain or difficulty breathing. 

Medical conditions associated with persistent hiccups聽

More serious medical conditions can cause longer-term hiccups, Dr. Shaker explains. Chronic hiccups are associated with several underlying disorders, ranging from brain tumors and strokes to pneumonia and pleurisy.  

Brain and nerve problems: Strokes and resulting neurological damage (especially a condition called Wallenberg syndrome) can cause persistent hiccups by affecting the area of the nervous system that controls the hiccup reflex. 

Heart or lung conditions: Heart attacks and lung conditions like pneumonia can trigger hiccups. 

Cancer: Some studies show that a small percentage of cancer patients may experience hiccups due to tumors or a side effect of medications used in treatment. Your doctor can help manage these side effects. 

Digestive system issues: Pancreatitis, irritation, infection or a dilated esophagus can contribute to hiccups. 

When to see a doctor for hiccups聽

Since chronic hiccup cases can persist for more than a month, it鈥檚 important to visit a doctor sooner rather than later. Persistent hiccups can be treated with medications such as chlorpromazine, a nerve blockade, or, in rare cases, surgery. 

If you do experience chronic hiccups, a visit to your doctor will help you get to the bottom of what鈥檚 causing them in the first place and find an appropriate treatment to make you feel more comfortable. 

Diagnosis

First, doctors will search for underlying causes by looking at your: 

  • Medical and medication history聽
  • Physical examination聽
  • Basic blood tests聽聽
  • Imaging studies such as a chest X-ray聽
  • Additional testing such as an upper endoscopy聽

鈥淭he first thing is to check all the basics,鈥 Dr. Shaker says. The goal is to rule out serious conditions before focusing on treating symptoms.  

Treatment options

Treatment approaches depend on how long your hiccups last. For brief hiccups, Dr. Shaker recommends at-home remedies: 

  • Holding your breath as long as you can聽
  • Performing the Valsalva maneuver (exhaling air or pushing air out while your nose and mouth are closed, such as during a bowel movement)聽
  • Drinking or gargling cold water聽
  • Biting on something sour like a lemon聽

For persistent hiccups, your doctor may consider medications, although some medications may have side effects of their own.  

In severe cases 鈥 intractable hiccups that significantly impact your quality of life 鈥 more advanced options may be considered, including nerve blocks, a breathing machine called a continuous positive airway pressure (CPAP) device, electrical stimulation of the diaphragm or even surgery. 

When dealing with hiccups, trust your instincts, Dr. Shaker says. If your hiccups last longer than what鈥檚 normal for you, have your doctor check them out. This personal approach ensures that potentially serious conditions aren鈥檛 overlooked.  

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At the 喵咪社区 Digestive Health Institute, our digestive health specialists treat a broad range of chronic and acute digestive problems and concerns. Our institute鈥檚 seven centers of excellence ensure you receive world-class, comprehensive, coordinated care for your digestive health.
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Curtis Biggs
Curtis Biggs is a digital writer for 喵咪社区.