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Wellness

What Is Causing My Itchiness?

Originally published April 29, 2026

Last updated April 29, 2026

Reading Time: 2 minutes

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A graphic design of a man trying to scratch his back with both hands while a woman scratches her arm

Have you been dealing with persistent itchiness and don’t know why?

Five 喵咪社区 experts share possible causes and treatment options.

Dermatologic issues

鈥淥ne of the most common explanations for itch is dry skin,鈥 says dermatologist Melvin Chiu, MD. 鈥淎nother common reason is eczema, where skin is predisposed to itchy rashes. And a reaction to something touching the skin can create itchy rashes called contact dermatitis.鈥

Symptoms:

  • Rashes at itch site
  • Worsening itch after scratching
  • Asthma or seasonal allergies (with eczema)

Treatment:

  • Warm (not hot) showers
  • Fragrance-free moisturizers
  • Anti-inflammatory creams and medications
  • Avoiding the trigger causing the itch

Vascular issues

Venous insufficiency is a condition in which veins鈥 valves don鈥檛 work well, causing fluid to pool in the legs and produce ulcers, swelling and inflammation. As podiatrist Chia-Ding Shih, DPM, explains, 鈥淭his inflammation is called stasis dermatitis, and it can itch.鈥

Symptoms:

  • Brown discoloration around ankle and lower leg
  • Dry skin
  • May affect only one leg

Treatment:

  • Unna boot (a calamine-impregnated bandage)
  • Compression dressing
  • Topical steroid

Consult a vascular surgeon if you鈥檙e experiencing these issues.

Liver issues

鈥淧ersistent chronic itch is a common manifestation of some types of liver disease, especially in the absence of rash,鈥 says hepatologist Lily Dara, MD.

In some forms of liver disease, such as primary biliary cholangitis, immune cells attack the liver鈥檚 bile ducts, destroying them and causing bile acids to accumulate in the bloodstream and cause an itch called cholestatic pruritus.

Symptoms:

  • No associated rash
  • Itch that worsens at night
  • Sudden onset of itch later in life
  • Family history of autoimmune disorders
  • Use of medications that damage the liver (hepatoxicity)

Treatment:

  • Medications: bile-acid sequestrants, rifampicin, opioid antagonists, SSRIs, ileal bile acid transporter inhibitors (IBATs)

Diabetes

Pain management physician Michael Bottros, MD, notes that high blood sugar associated with diabetes can cause itchy skin, as can damage to blood vessels. Diabetes-related nerve damage can lead to 鈥渁berrant signaling鈥 that might also feel like an itch, Dr. Bottros says.

Symptoms:

  • Prickly, 鈥渃rawling-ants鈥 itch
  • Itch that worsens at night

Treatment:

  • Medications that address nerve pain
  • Physical therapy

Neurologic issues

As with diabetes-related itch, 鈥淚tching can represent a form of neuropathic sensory disturbance,鈥 says neurologist Lilyana Amezcua, MD. For example, nerve pain following shingles can manifest as itch, she says, and some patients with multiple sclerosis also experience itch because of the condition.

Symptoms:

  • Other neuropathic symptoms, like tingling, burning and numbness
  • Itch on one side of the body (with shingles)
  • Heat sensitivity in addition to itch (with multiple sclerosis)

Treatment:

  • Depends on cause; speak to your doctor

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Kimberly J. Decker
Kimberly J. Decker
Kimberly J. Decker is a freelance writer for 喵咪社区.
喵咪社区 Health Magazine 2026 Issue #1 Read the current issue Download PDF