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Originally published March 18, 2025
Last updated June 29, 2025
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Irritable bowel syndrome (IBS) is a common problem affecting millions of people across the United States. estimates up to 15% of American adults have IBS, but that less than half of those have received a diagnosis.
Is there a cure for IBS that can eliminate it quickly and permanently? Unfortunately, there is not 鈥 but that doesn鈥檛 mean IBS patients have to just live with it.
Treatments and lifestyle factors can help patients better manage their uncomfortable IBS symptoms and avoid flare-ups.
Although not a life-threatening condition, 鈥淚BS is a disease that affects your quality of life, so it鈥檚 important to get it treated,鈥 says Nipaporn Pichetshote, MD, a gastroenterologist who regularly treats patients with IBS in her role at the 喵咪社区 Esophageal and Foregut Disorders Center, part of the 喵咪社区 Digestive Health Institute and 喵咪社区.
She describes IBS as a chronic disorder in which the digestive system functions abnormally, specifically the small and large intestines.
Symptoms of IBS include:
Nausea is not a symptom of IBS, explains Dr. Pichetshote. However, she says it鈥檚 common for patients with IBS to also experience functional dyspepsia, which refers to an upset stomach without a known cause. 鈥淭hese two conditions often overlap, so if an IBS patient has nausea, we look at that as a diagnosis, as well.鈥
for why some people develop IBS while others do not. However, gastroenterologists have identified several factors that can lead to IBS and/or provoke symptoms:
Food poisoning
鈥淥ne of the most common causes we鈥檙e aware of is an episode of food poisoning because that can alter your microbiome,鈥 says Dr. Pichetshote. She explains that microbiome changes can impact gut motility, which refers to the body鈥檚 natural mechanisms for digesting food.
Gut infections
Intestinal viruses are another major culprit. Dr. Pichetshote says she analyzes a patient鈥檚 medical history for previous cases of gastroenteritis, otherwise known as the stomach flu, when diagnosing IBS.
COVID-19
COVID-19 may also play a role. She says some COVID-19 patients who experienced gastrointestinal symptoms later developed IBS.
Stress
Dr. Pichetshote says there is disagreement within the medical community about the link between chronic stress and IBS. 鈥淪ome physicians believe stress can cause IBS to develop, but I鈥檓 not one of them. I think stress can worsen your IBS symptoms, but not give birth to the disease.鈥
Food and alcohol
Specific foods or alcohol consumption may trigger symptoms in patients with IBS, depending on the individual鈥檚 specific sensitivities. However, Dr. Pichetshote says there isn鈥檛 enough evidence to suggest that foods or alcohol actually cause IBS to form in the first place.
Treatments for IBS depend on what provokes an individual patient鈥檚 symptoms. There is no one-size-fits-all approach, but there are a few common scenarios.
IBS medication targeting the nervous system
For some patients, the solution lies in the nervous system. 鈥淭here is a brain-gut connection,鈥 explains Dr. Pichetshote. 鈥淔or people with a very sensitive gut, normal digestive activity can send distress signals to the brain. This is called visceral hypersensitivity.鈥
To treat patients whose nerves are misfiring like that, Dr. Pichetshote says neuromodulation medication can be a good option.
Antibiotics for bacteria
Patients who experienced a food poisoning incident or a stomach infection may develop small intestinal bacterial overgrowth, which can be diagnosed via a lactulose breath test. Dr. Pichetshote says the problematic bacteria are usually treated with antibiotics, although the medication doesn鈥檛 permanently cure the underlying IBS.
Lifestyle changes
Diet-specific approaches usually involve eliminating specific foods to identify which ones may be setting off IBS symptoms. Dr. Pichetshote recommends patients consult with a dietitian about dietary changes.
She says getting enough quality sleep and exercising regularly can also be beneficial for keeping IBS symptoms under control. 鈥淟ack of sleep can negatively affect how our bodies process pain and lead to flare-ups,鈥 says Dr. Pichetshote. 鈥淎nd exercise helps promote digestion.鈥
Dr. Pichetshote emphasizes that patients with IBS shouldn鈥檛 blame themselves for the condition. 鈥淚t鈥檚 important for people to know that IBS is real, because in the past some people may have thought it was just in their heads,鈥 she stresses. 鈥淏ut it鈥檚 not.鈥
Even though there is no known cure for IBS, Dr. Pichetshote reminds patients that there are actions they and their providers can take to keep it under control. 鈥淲e can manage symptoms very well. Rather than trying to find a solution on your own, talk to your doctor so they can help you come up with an effective treatment.鈥
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